Publications
Selectivity in subunit composition of Ena/VASP tetramers. Biosci Rep. 2015;35(5).
. Studying Cellular Signal Transduction with OMIC Technologies. J Mol Biol. 2015;427(21):3416-40.
. Targeting autocrine HB-EGF signaling with specific ADAM12 inhibition using recombinant ADAM12 prodomain. Sci Rep. 2015;5:15150.
. Uncharged Helical Modular Polypeptide Hydrogels for Cellular Scaffolds. Biomacromolecules. 2015;16(12):3774-83.
. Adaptive protein and phosphoprotein networks which promote therapeutic sensitivity or acquired resistance. Biochem Soc Trans. 2014;42(4):758-64.
. Addressing genetic tumor heterogeneity through computationally predictive combination therapy. Cancer Discov. 2014;4(2):166-74.
. Analysis of growth factor signaling in genetically diverse breast cancer lines. BMC Biol. 2014;12:20.
. Building robust transcriptomes with master splicing factors. Cell. 2014;159(3):487-98.
. Cell-specific labeling enzymes for analysis of cell-cell communication in continuous co-culture. Mol Cell Proteomics. 2014;13(7):1866-76.
. Co-regulation of primary mouse hepatocyte viability and function by oxygen and matrix. Biotechnol Bioeng. 2014;111(5):1018-27.
. Ena/VASP regulates mDia2-initiated filopodial length, dynamics, and function. Mol Biol Cell. 2014;25(17):2604-19.
. Equilibrium and dynamic design principles for binding molecules engineered for reagentless biosensors. Anal Biochem. 2014;460:9-15.
. From breaking bad to worse: exploiting homologous DNA repair deficiency in cancer. Cancer Discov. 2014;4(5):516-8.
. Intratumor heterogeneity alters most effective drugs in designed combinations. Proc Natl Acad Sci U S A. 2014;111(29):10773-8.
. A nanoparticle-based combination chemotherapy delivery system for enhanced tumor killing by dynamic rewiring of signaling pathways. Sci Signal. 2014;7(325):ra44.
. Qualitatively different T cell phenotypic responses to IL-2 versus IL-15 are unified by identical dependences on receptor signal strength and duration. J Immunol. 2014;192(1):123-35.
. Quantification of protein kinase enzymatic activity in unfractionated cell lysates using CSox-based sensors. Curr Protoc Chem Biol. 2014;6(3):135-56.
. Quantitative analysis of signaling networks across differentially embedded tumors highlights interpatient heterogeneity in human glioblastoma. J Proteome Res. 2014;13(11):4581-93.
. Rbfox2 controls autoregulation in RNA-binding protein networks. Genes Dev. 2014;28(6):637-51.
. Reproducible automated phosphopeptide enrichment using magnetic TiO2 and Ti-IMAC. Anal Chem. 2014;86(20):10296-302.
. Selective mitogen activated protein kinase activity sensors through the application of directionally programmable D domain motifs. Biochemistry. 2014;53(36):5771-8.
. Sharing information to reconstruct patient-specific pathways in heterogeneous diseases. Pac Symp Biocomput. 2014;:39-50.
. SirT1 is required in the male germ cell for differentiation and fecundity in mice. Development. 2014;141(18):3495-504.
. System level dynamics of post-translational modifications. Curr Opin Biotechnol. 2014;28C:83-87.
. Tailoring chimeric ligands for studying and biasing ErbB receptor family interactions. Angew Chem Int Ed Engl. 2014;53(10):2662-6.
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