Publications
VASP is a CXCR2-interacting protein that regulates CXCR2-mediated polarization and chemotaxis. J Cell Sci. 2009;122(Pt 11):1882-94.
. Vascular endothelial growth factor (VEGF) and platelet (PF-4) factor 4 inputs modulate human microvascular endothelial signaling in a three-dimensional matrix migration context. Mol Cell Proteomics. 2013;12(12):3704-18.
. Understanding resistance to combination chemotherapy. Drug Resist Updat. 2012;15(5-6):249-57.
. Understanding effects of matrix protease and matrix organization on directional persistence and translational speed in three-dimensional cell migration. Ann Biomed Eng. 2007;35(1):91-100.
. Uncovering therapeutic targets for glioblastoma: a systems biology approach. Cell Cycle. 2007;6(22):2750-4.
. Uncharged Helical Modular Polypeptide Hydrogels for Cellular Scaffolds. Biomacromolecules. 2015;16(12):3774-83.
. Ulcerative colitis and autoimmunity induced by loss of myeloid alphav integrins. Proc Natl Acad Sci U S A. 2007;104(40):15823-8.
. Tumor microenvironment of metastasis in human breast carcinoma: a potential prognostic marker linked to hematogenous dissemination. Clin Cancer Res. 2009;15(7):2433-41.
. Tumor Cell-Driven Extracellular Matrix Remodeling Drives Haptotaxis during Metastatic Progression. Cancer Discov. 2016;6(5):516-31.
. Training signaling pathway maps to biochemical data with constrained fuzzy logic: quantitative analysis of liver cell responses to inflammatory stimuli. PLoS Comput Biol. 2011;7(3):e1001099.
. Towards a rigorous assessment of systems biology models: the DREAM3 challenges. PLoS One. 2010;5(2):e9202.
. Toward quantitative phosphotyrosine profiling in vivo. Semin Cell Dev Biol. 2012;23(8):854-62.
. Tks5 and SHIP2 regulate invadopodium maturation, but not initiation, in breast carcinoma cells. Curr Biol. 2013;23(21):2079-89.
. Three-kinase inhibitor combination recreates multipathway effects of a geldanamycin analogue on hepatocellular carcinoma cell death. Mol Cancer Ther. 2009;8(8):2183-92.
. A Thermodynamic-Based Interpretation of Protein Expression Heterogeneity in Different Glioblastoma Multiforme Tumors Identifies Tumor-Specific Unbalanced Processes. J Phys Chem B. 2016;.
. Targeting H3K4 trimethylation in Huntington disease. Proc Natl Acad Sci U S A. 2013;110(32):E3027-36.
. Targeting autocrine HB-EGF signaling with specific ADAM12 inhibition using recombinant ADAM12 prodomain. Sci Rep. 2015;5:15150.
. Tailoring chimeric ligands for studying and biasing ErbB receptor family interactions. Angew Chem Int Ed Engl. 2014;53(10):2662-6.
. Systematic phosphorylation analysis of human mitotic protein complexes. Sci Signal. 2011;4(198):rs12.
. Systematic discovery of in vivo phosphorylation networks. Cell. 2007;129(7):1415-26.
. System level dynamics of post-translational modifications. Curr Opin Biotechnol. 2014;28C:83-87.
. A system for Cre-regulated RNA interference in vivo. Proc Natl Acad Sci U S A. 2008;105(37):13895-900.
. Swimming upstream: identifying proteomic signals that drive transcriptional changes using the interactome and multiple "-omics" datasets. Methods Cell Biol. 2012;110:57-80.
. Suppression of non-small cell lung tumor development by the let-7 microRNA family. Proc Natl Acad Sci U S A. 2008;105(10):3903-8.
. Studying Cellular Signal Transduction with OMIC Technologies. J Mol Biol. 2015;427(21):3416-40.
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