Publications
ADAM8 as a drug target in pancreatic cancer. Nat Commun. 2015;6:6175.
. MARQUIS: a multiplex method for absolute quantification of peptides and posttranslational modifications. Nat Commun. 2015;6:5924.
. Quantitative Profiling of Lysine Acetylation Reveals Dynamic Crosstalk between Receptor Tyrosine Kinases and Lysine Acetylation. PLoS One. 2015;10(5):e0126242.
. SAMNetWeb: identifying condition-specific networks linking signaling and transcription. Bioinformatics. 2015;31(7):1124-6.
. Studying Cellular Signal Transduction with OMIC Technologies. J Mol Biol. 2015;427(21):3416-40.
. Adaptive protein and phosphoprotein networks which promote therapeutic sensitivity or acquired resistance. Biochem Soc Trans. 2014;42(4):758-64.
. Analysis of growth factor signaling in genetically diverse breast cancer lines. BMC Biol. 2014;12:20.
. Cell-specific labeling enzymes for analysis of cell-cell communication in continuous co-culture. Mol Cell Proteomics. 2014;13(7):1866-76.
. Ena/VASP regulates mDia2-initiated filopodial length, dynamics, and function. Mol Biol Cell. 2014;25(17):2604-19.
. Qualitatively different T cell phenotypic responses to IL-2 versus IL-15 are unified by identical dependences on receptor signal strength and duration. J Immunol. 2014;192(1):123-35.
. Quantitative analysis of signaling networks across differentially embedded tumors highlights interpatient heterogeneity in human glioblastoma. J Proteome Res. 2014;13(11):4581-93.
. Activation of the yeast Hippo pathway by phosphorylation-dependent assembly of signaling complexes. Science. 2013;340(6134):871-5.
. The bromodomain protein Brd4 insulates chromatin from DNA damage signalling. Nature. 2013;498(7453):246-50.
. Linking proteomic and transcriptional data through the interactome and epigenome reveals a map of oncogene-induced signaling. PLoS Comput Biol. 2013;9(2):e1002887.
. Models of signalling networks - what cell biologists can gain from them and give to them. J Cell Sci. 2013;126(Pt 9):1913-21.
. Profiles of Basal and stimulated receptor signaling networks predict drug response in breast cancer lines. Sci Signal. 2013;6(294):ra84.
. The receptor AXL diversifies EGFR signaling and limits the response to EGFR-targeted inhibitors in triple-negative breast cancer cells. Sci Signal. 2013;6(287):ra66.
. Simultaneous reconstruction of multiple signaling pathways via the prize-collecting steiner forest problem. J Comput Biol. 2013;20(2):124-36.
. Combined experimental and computational analysis of DNA damage signaling reveals context-dependent roles for Erk in apoptosis and G1/S arrest after genotoxic stress. Mol Syst Biol. 2012;8:568.
. Computational approaches for analyzing information flow in biological networks. Sci Signal. 2012;5(220):re1.
. Expanding applications of chemical genetics in signal transduction. Cell Cycle. 2012;11(10):1903-9.
. Interrogating signaling nodes involved in cellular transformations using kinase activity probes. Chem Biol. 2012;19(2):210-7.
. Mena binds α5 integrin directly and modulates α5β1 function. J Cell Biol. 2012;198(4):657-76.
. Molecular characterization of EGFR and EGFRvIII signaling networks in human glioblastoma tumor xenografts. Mol Cell Proteomics. 2012;11(12):1724-40.
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